Betwyll can be used in universities as a support to traditional didactics and as a space for collaborative learning. Within Betwyll it is in fact possible to create ad hoc virtual classrooms where students of the same course can interact among them and with the professor, in a private space built to address specific needs and objectives. To date, Betwyll has been used at the universities of Aalborg (Denmark), Edinburgh (Scotland), Ghent (Belgium), Harvard (USA), Indiana (USA), New York (USA), Toronto (Canada), Toronto Mississauga (Canada), York (Canada) and by Nexa Center for Internet and Society (Politecnico di Torino, Italy). It was also subject of researches by the universities of Cardiff (Wales) and Pavia (Italy).